Recent advances in laparoscopic instruments and techniques allow transabdominal transection of levator muscles under direct vision. Therefore, a laparoscopic-dominant APR becomes possible. This approach offers a transabdominal individualized transection of levator muscle, lowers the meeting level down to the ischiorectal fat, and at the same time provides guidance for the extent of perineal resection. The resection line therefore is predominantly determined by the laparoscopic procedure, rather
Introduction: Human Keratinocyte Growth Factor (KGF), also known as Fibroblast Growth Factor (FGF) 7, is a single chain, heparin-binding FGF family protein. KGF is produced by cells of mesenchymal origin yet has its effect on epithelial cell subpopulations, keratinocytes for example, which express the KGF cell surface receptor (KGF-R) which has tyrosine kinase activity. It is thought to be a paracrine promoter of epithelial cell proliferation and differentiation. KGF also plays a role in the epi
Background: Laparoscopic surgery for colorectal cancer in elderly and high-risk patients has proven to be safe and beneficial, with more favorable short-term results. This study evaluated the impact of co-morbidities in the short-term outcomes of elderly patients undergoing laparoscopic resection for colorectal cancer.
Methods: After IRB approval, 303 consecutive patients >65 years of age who underwent curative laparoscopic resection for colorectal cancer between January 2000 and June 2014 were
INTRODUCTION: Restorative proctocolectomy (RP) with ileal pouch-anal anastomosis (IPAA) is the operation of choice for patients with familial adenomatous polyposis (FAP) and a profuse colorectal phenotype. Laparoscopic techniques have potential advantages for young patients undergoing colectomy and have been applied to this surgery. However, data confirming these potential benefits are limited. In this study, we aim to compare the short-term outcomes of open versus laparoscopic RP in patients wi
Introduction: Our objective was to evaluate the feasibility and efficacy of Single-incision Laparoscopic Colectomy (SILC) in obese patients. SILC is safe and feasible for treating benign and malignant colorectal disease. SILC offers several patient-related benefits over multiport laparoscopy. However, its use in obese patients has been limited due to concerns of greater technical difficulty, oncologic compromise, and higher complication and conversion rates.
Methods and Procedures: Review of a